Active NCI RFAs:  FY 2023  FY 2022  FY 2021  FY 2020 | Archive RFAs | Active PAs
Current and Recent Requests for Applications (RFA's)
RFA's that are active or have expired within the last 3 months (and associated notices)
 
2023 Trans-NIH Requests for Applications (RFA's)
RFA No. and TitleStatus - Expiration
DA23-051 HEAL Initiative: Preventing Opioid Misuse and Co-Occurring Conditions by Intervening on Social Determinants (R01 - Clinical Trials Optional)ACTIVE - FEB 03, 2023
DA23-048 HEAL Initiative: Research Studies to Develop and Implement Interventions to Prevent Opioid Misuse in Community Health Centers (R61/R33 Clinical Trial Required)ACTIVE - NOV 09, 2022
DA23-041 HEAL Initiative: Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy (MIRHIQL) (R01 Clinical Trial Required)ACTIVE - OCT 04, 2022
HL23-007 Limited Competition: Stimulating Access to Research in Residency Transition Scholar (StARRTS) (K38 Clinical Trial Not Allowed)ACTIVE - JAN 11, 2025
HL23-006 Stimulating Access to Research in Residency (StARR) (R38)ACTIVE - MAY 17, 2024
NR23-001 HEAL Initiative: Prevention and Management of Chronic Pain in Rural Populations (UG3/UH3, Clinical Trials Required)ACTIVE - NOV 22, 2022
NS23-007 HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)ACTIVE - APR 05, 2025
NS23-003 HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)ACTIVE - JUN 10, 2025
 
 
 
 
2022 Requests for Applications (RFA's)
RFA No. and TitleStatus - Expiration
CA22-055 Cancer Prevention-Interception Targeted Agent Discovery Program (CAP-IT) Centers (U54 Clinical Trial Not Allowed)ACTIVE - NOV 22, 2022
CA22-054 The Early Detection Research Network: Clinical Validation Centers (U01 Clinical Trial Optional)EXPIRED - SEP 20, 2022
CA22-050 NCI Cancer Moonshot Scholars Diversity Program (CMSDP) (R01 Clinical Trial Optional)ACTIVE - FEB 07, 2024
CA22-046 Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)ACTIVE - OCT 04, 2022
CA22-045 NCI Outstanding Investigator Award (R35 Clinical Trial Optional)ACTIVE - NOV 08, 2024
CA22-041 The NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Clinical Trial Not Allowed)ACTIVE - NOV 19, 2022
CA22-040 The Early Detection Research Network: Biomarker Characterization Centers (U2C Clinical Trial Not Allowed)EXPIRED - SEP 09, 2022
CA22-039 The Early Detection Research Network: Clinical Validation Centers (U01 Clinical Trial Optional)EXPIRED - SEP 09, 2022
CA22-038 Limited Competition: Cancer Immune Monitoring and Analysis Centers (CIMACs) and Cancer Immunologic Data Center (CIDC) (U24 Clinical Trial Not Allowed)ACTIVE - OCT 25, 2022
CA22-037 NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Basic Experimental Studies with Humans Required)ACTIVE - MAR 01, 2023
CA22-036 NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required)ACTIVE - MAR 01, 2023
CA22-035 NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)ACTIVE - MAR 01, 2023
CA22-032 Consortium on Translational Research in Early Detection of Liver Cancer: Data Management and Coordinating Center (U24 Clinical Trial Not Allowed)ACTIVE - NOV 08, 2022
CA22-031 Consortium on Translational Research in Early Detection of Liver Cancer: Translational Research Centers (U01 Clinical Trial Optional)ACTIVE - NOV 08, 2022
CA22-030 Cancer Adoptive Cellular Therapy Network (Can-ACT) Coordinating Center (U24 Clinical Trial Not Allowed)ACTIVE - OCT 29, 2022
CA22-029 Cancer Adoptive Cellular Therapy Network (Can-ACT) for Pediatric Cancers (UG3/UH3 Clinical Trial Required)ACTIVE - JUL 01, 2023
CA22-028 Cancer Adoptive Cellular Therapy Network (Can-ACT) for Adult Cancers (UG3/UH3 Clinical Trial Required)ACTIVE - JUL 01, 2023
CA22-027 Research to Understand and Address the Survivorship Needs of Individuals Living with Advanced Cancer (R01 Clinical Trial Optional)ACTIVE - SEP 30, 2023
CA22-026 Limited Competition: A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research (U24 Clinical Trial Not Allowed)EXPIRED - SEP 16, 2022
CA22-025 SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization (R44 Clinical Trial Optional)EXPIRED - AUG 06, 2022
CA22-024 Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)ACTIVE - NOV 18, 2022
CA22-023 Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)ACTIVE - NOV 18, 2022
CA22-022 Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)ACTIVE - NOV 18, 2022
CA22-021 Development of Innovative Informatics Methods and Algorithms for Cancer Research and Management (R21 Clinical Trial Optional)ACTIVE - NOV 18, 2022
CA22-019 Global Implementation Science for Equitable Cancer Control (GlobalISE Cancer Control, U54 Clinical Trial Optional)ACTIVE - NOV 09, 2022
CA22-017 Small Business Transition Grant For Early Career Scientists (R42 Clinical Trial Not Allowed)EXPIRED - AUG 23, 2022
CA22-016 Pediatric Immunotherapy Network (PIN) (U01 Clinical Trial Optional)EXPIRED - SEP 28, 2022
CA22-015 Cancer Control Research in Persistent Poverty Areas (U54 Clinical Trial Optional)EXPIRED - JUL 07, 2022
CA22-013 PDX Data Commons and Coordinating Center (PDCCC) for the PDX Development and Trial Centers Research Network (PDXNet) (U24 Clinical Trial Not Allowed)ACTIVE - NOV 02, 2022
CA22-012 Patient Derived Xenograft (PDX) Development and Trial Centers (PDTCs) Network (U54 Clinical Trial Not Allowed)ACTIVE - NOV 02, 2022
CA22-010 Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U2C Clinical Trial Optional)EXPIRED - SEP 23, 2022
CA22-009 Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P50 Clinical Trial Optional)EXPIRED - SEP 23, 2022
CA22-008 Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P01 Clinical Trial Optional)EXPIRED - SEP 23, 2022
CA22-007 Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U54 Clinical Trials Optional)EXPIRED - SEP 23, 2022
CA22-006 Revision Applications for Incorporation of Novel NCI- Supported Technology to Accelerate Cancer Research (U01 Clinical Trial Optional)EXPIRED - SEP 23, 2022
CA22-005 Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trial Optional)EXPIRED - SEP 23, 2022
CA22-004 Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)EXPIRED - SEP 23, 2022
CA22-003 Innovative Biospecimen Science Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)EXPIRED - SEP 23, 2022
CA22-002 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)EXPIRED - SEP 23, 2022
CA22-001 Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)EXPIRED - SEP 23, 2022
 
2022 Trans-NIH Requests for Applications (RFA's)
RFA No. and TitleStatus - Expiration
EB22-002 HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)ACTIVE - JUN 18, 2025
ES22-003 Research Coordinating Center to Support Climate Change and Health Community of Practice (U24 Clinical Trial Not Allowed)EXPIRED - AUG 26, 2022
HG22-010 Multi-Omics for Health and Disease - Data Analysis and Coordination Center (U01 Clinical Trial Not Allowed)ACTIVE - NOV 19, 2022
HG22-009 Multi-Omics for Health and Disease - 'Omics Production Centers (U01 Clinical Trial Not Allowed)ACTIVE - NOV 19, 2022
HG22-008 Multi-Omics for Health and Disease - Disease Study Sites (U01 Clinical Trial Optional)ACTIVE - NOV 19, 2022
MD22-008 Understanding and Addressing Misinformation among Populations that Experience Health Disparities (R01 - Clinical Trials Optional)ACTIVE - NOV 14, 2022
MH22-130 Integrating Mental Health Care into Health Care Systems in Low- and Middle-Income Countries (R01 Clinical Trial Optional)EXPIRED - AUG 05, 2022
NS22-070 HEAL Initiative: Development and Validation of Non-Rodent Mammalian Models of Pain(R01 Clinical Trial Not Allowed)ACTIVE - MAR 07, 2024
NS22-053 NIH HEAL Initiative: Coordinated Approaches to Pain Care in Health Care Systems (UG3/UH3 - Clinical Trial Optional)ACTIVE - NOV 05, 2022
NS22-052 HEAL Initiative: Team Research for Initial Translational Efforts in Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed)ACTIVE - OCT 11, 2023
NS22-050 HEAL Initiative: Discovery of Biomarkers and Biomarker Signatures to Facilitate Clinical Trials for Pain Therapeutics (UG3/UH3 Clinical Trial Optional)ACTIVE - FEB 24, 2023
NS22-034 HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)ACTIVE - DEC 07, 2024
NS22-021 HEAL Initiative: Human Pain-associated Genes and Cells Data Coordination and Integration Center (U24 Clinical Trial Not Allowed)ACTIVE - OCT 12, 2022
NS22-018 HEAL Initiative: Discovery and Functional Evaluation of Human Pain-associated Genes and Cells (U19 Clinical Trial Not Allowed)ACTIVE - MAR 10, 2023
OD22-019 Limited Competition: Environmental influences on Child Health Outcomes (ECHO) Cohort Study Sites for Pediatric Follow Up. Clinical Trial Not Allowed (UG3/UH3)ACTIVE - NOV 22, 2022
OD22-018 Limited Competition: Environmental influences on Child Health Outcomes (ECHO) Pregnancy and Pediatric Cohort Study Sites. Clinical Trial Not Allowed (UG3/UH3)ACTIVE - NOV 22, 2022
OD22-017 Open Competition: Environmental influences on Child Health Outcomes (ECHO) Pregnancy Cohort Study Sites. Clinical Trial Not Allowed (UG3/UH3)ACTIVE - NOV 22, 2022
OD22-010 Clinical Trials Development for Co-Occurring Conditions in Individuals with Down syndrome: Phased Awards for INCLUDE (R61/R33 Clinical Trial Required)ACTIVE - JUL 02, 2024
OD22-009 Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed)ACTIVE - JUL 02, 2024
OD22-008 Small Research Grants for Analysis, Curation, and/or Sharing of Down syndrome-related Research Data for the INCLUDE Project (R03 Clinical Trial Not Allowed)ACTIVE - JUL 02, 2024
OD22-007 INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed)ACTIVE - JUL 02, 2024
OD22-004 Tobacco Centers of Regulatory Science (TCORS) for Research Relevant to the Family Smoking Prevention and Tobacco Control Act (U54 Clinical Trial Optional)EXPIRED - JUL 15, 2022
RM22-008 NIH Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program: FIRST Cohort (U54 Clinical Trial Optional)EXPIRED - JUL 13, 2022
TR22-013 Emergency Awards: HEAL Initiative- New Innovator Award (DP2 Clinical Trial Not Allowed)ACTIVE - MAY 23, 2023
TR22-011 Emergency Awards: HEAL Initiative-Early-Stage Discovery of New Pain and Opioid Use Disorder Targets Within the Understudied Druggable Proteome (R21 Clinical Trial Not Allowed)ACTIVE - MAY 23, 2023
 
 
 
 
2021 Requests for Applications (RFA's)
RFA No. and TitleStatus - Expiration
CA21-048 Research Centers for Cancer Systems Biology (U54 Clinical Trial Not Allowed)ACTIVE - OCT 20, 2022
CA21-020 National Cancer Institute Youth Enjoy Science Research Education Program (R25 Clinical Trial Not Allowed)ACTIVE - SEP 29, 2023
 
2021 Trans-NIH Requests for Applications (RFA's)
RFA No. and TitleStatus - Expiration
HG21-001 Technology Development for Single-Molecule Protein Sequencing (R01 Clinical Trial not allowed)ACTIVE - JUN 16, 2023
OD21-007 INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Exploratory/Developmental Research Grant Award (R21 Clinical Trial Not Allowed)ACTIVE - JUL 04, 2024
OD21-004 Maximizing the Scientific Value of Existing Biospecimen Collections (R21 Clinical Trial Not Allowed)ACTIVE - MAR 09, 2023
OD21-003 Secondary Analyses of Existing Datasets of Tobacco Use and Health (R21 Clinical Trial Not Allowed)ACTIVE - MAR 09, 2023
OD21-002 Tobacco Regulatory Science (R01 Clinical Trial Optional)ACTIVE - FEB 15, 2023
 
 
 
 
2020 Trans-NIH Requests for Applications (RFA's)
RFA No. and TitleStatus - Expiration
NS20-011 HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Not Allowed)EXPIRED - SEP 09, 2022
NS20-010 HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Required)EXPIRED - SEP 09, 2022
NS20-009 HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)EXPIRED - SEP 09, 2022
NS20-008 HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Required)EXPIRED - SEP 09, 2022
OD20-011 Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01 - Independent Clinical Trial Required)EXPIRED - JUL 11, 2022
OD20-010 Pathway to Independence Award in Tobacco Regulatory Research (K99/R00 - Independent Clinical Trial Required)EXPIRED - JUL 11, 2022
OD20-009 Pathway to Independence Award in Tobacco Regulatory Research (K99/R00 - Independent Clinical Trial Not Allowed)EXPIRED - JUL 11, 2022
OD20-008 Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01 - Independent Clinical Trial Not Allowed)EXPIRED - JUL 11, 2022