For additional information, visit the U.S. Department of Veterans Affairs website.
Provide a concise description of the proposed procedures to be used that involve vertebrate animals. Identify the species, strains, ages, sex, and total number of animals by species to be used. If dogs or cats are proposed, provide the source of the animals.
Provide justification that the species are appropriate for the proposed research. Explain why the research goals cannot be accomplished using an alternative model (e.g., computational, human, invertebrate, in vitro).
Describe the interventions to minimize discomfort, distress, pain, and injury. These include analgesia, anesthesia, sedation, palliative care, and humane endpoints.
Provide a justification for methods of euthanasia that are not consistent with the American Veterinary Medical Association (AVMA) Guidelines for the Euthanasia of Animals.
For additional information, visit the Office of Laboratory Animal Welfare – Vertebrate Animals Section webpage and the "General Instructions for NIH and Other PHS Agencies SF424(R&R) Application Packages" sections G.210 - PHS 398 Cover Page Supplement Form and G.220 - R&R Other Project Information Form.
For additional information, visit the eRA Virtual Meeting webpage.