'T' Terms

Targeted Research
Research funded as a result of an Institute set aside of dollars for a specific scientific area. Institutes solicit applications using research initiatives (RFAs for grants, RFPs for contracts). Targeted research applications are reviewed by chartered peer review committees within Institutes. The opposite is Investigator-Initiated Research.

Quoted from the NIH OER Glossary & Acronym List.

Also called "Solicited Research".

See Also: Investigator-Initiated Research
Targeted/Planned Enrollment Data
Provides race and ethnicity data for projected number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.

Quoted from the NIH OER Glossary & Acronym List.

Task Order
"Task order" means an order for services placed against an established contract or with Government sources.

Quoted from §2.101 of the Federal Acquisition Regulation.

Task-Order Contract
"Task-order contract" means a contract for services that does not procure or specify a firm quantity of services (other than a minimum or maximum quantity) and that provides for the issuance of orders for the performance of tasks during the period of the contract.

Quoted from the §16.501 of the Federal Acquisition Regulation.

See Also: Delivery-Order Contract ;  Indefinite Quantity Contract
Technical Evaluation Criteria (Contracts)
See: Technical Evaluation Factors
Technical Evaluation Factors
The PO must develop evaluation factors in consultation with review staff and submit them to the CO in the AP/RFC for inclusion in the RFP. Development of these factors and the assignment of the relative importance or weight to each require the exercise of judgment on a case-by-case basis because they must be tailored to the requirements of the individual acquisition. Because the factors will serve as a standard against which all proposals will be evaluated, it is imperative that staff choose them carefully to emphasize those considered to be critical in the selection of a contractor. The final evaluation factors contained in the RFP cannot be changed except by a formal amendment issued by the CO. No factors other than those set forth in the RFP may be used to evaluate proposals. The evaluation factors must be clear, concise, and fair so all potential offerors are fully aware of the bases for proposal evaluation. See HHSAR 315.204-5(c) for more details.

Quoted from NIH Policy Manual Chapter 6315-1 §E.1.e.(3).

See Also: Review Critera for Contract Projects and Proposals
Technical Evaluation Panel
See: Special Emphasis Panel
Technical Evaluation Report TER  
A report prepared and furnished to the Contract Officer (CO) by the Scientific Review Officer (SRO) and maintained as a permanent record in the contract file. The report must reflect the ranking of the proposals and identify each proposal as acceptable or unacceptable. The report also must include a narrative evaluation specifying the strengths and weaknesses of each proposal, a copy of each signed rating sheet, and any reservations, qualifications, or areas to be addressed that might bear upon the selection of sources for negotiation and award. Concrete technical reasons supporting a determination of unacceptability with regard to any proposal must be included. The report also must include specific points and questions, which are to be raised in discussions or negotiations.

Quoted from NIH Policy Manual Chapter 6315-1 §H.20.

Technical Proposal Evaluation
The selected SRG performs the technical evaluation of all proposals in response to an RFP, guided by the SRA. Program staff or designees should attend review meetings within their respective responsibilities and provide technical, administrative, and/or program information essential for adequate review and evaluation. However, they may not be a member of the SRG nor join the technical discussions or recommendations concerning the proposals. All staff must avoid evaluative comments or indications of bias toward individual proposals. However, staff should privately alert the SRA when it appears that the reviewers have overlooked information contained in a proposal. Other program staff may attend review meetings with SRA concurrence.

Quoted from NIH Policy Manual Chapter 6315-1 §E.2.

See Also: Review Critera for Contract Projects and Proposals ;  Scientific Review Group
Technical Proposal Instructions
RFP Section L, Instructions, Conditions, and Notices to Offerors, informs prospective offerors that the proposal must be prepared in two parts: a technical and a business proposal, each part separate and complete in itself so evaluations of each may be performed independently of, and concurrently with, the other. RFP instructions must be tailored on a case-by-case basis to ensure appropriate consideration of the specific acquisition, for example: capability to meet recruitment goals, model protocols and prior relative experience of the named staff. Technical proposals may include proposed direct costs. Offerors' estimates of personnel, equipment, facilities and other project costs are helpful indicators of their basic understanding of the RFP requirements. ICs may set page limits for technical proposals, resumes or other parts of the proposal.

Quoted from the NIH Policy Manual Chapter 6315-1 §E.1.e.(2).

Technology Transfer
Sharing of knowledge and facilities among Federal laboratories, industry, universities, Government, and others to make federally generated scientific and technological advances accessible to private industry and State and local Governments. Go to NIH Office of Technology Transfer.

Quoted from the NIH OER Glossary & Acronym List.

Technology Transfer Branch (NCI) TTB  
See: Technology Transfer Center
Technology Transfer Center TTC  
NCI's Technology Transfer Center (TTR) builds partnerships and fosters collaboration agreements between NIH scientists, universities, non-profits, and industry to commercialize NIH inventions, and supports research and development that benefits public health.
Temporary Duty Location TDY  
A place, away from the employee's official duty station where the employee is authorized to travel and conduct Government business.

Quoted from the NIH Policy Manual Chapter 1500-1 § E.24.

Temporary Member
When NIH staff determines there is need for additional expertise on Scientific Review Groups, they may invite appropriate experts to serve as special reviewers.

These special reviewers are designated as "temporary members" for the meeting in which they participate and have the rights and obligations of regular members during that meeting; however, they do not contribute to a quorum.

Excerpted from NIH Policy Manual Chapter 54705.

See Also: Fully Participating Reviewer
Termination
The ending of a Federal award, in whole or in part at any time prior to the planned end of period of performance.

Quoted from the NIH OER Glossary & Acronym List.

Termination for Convenience, Contracts
“Termination for convenience” means the exercise of the Government’s right to completely or partially terminate performance of work under a contract when it is in the Government’s interest.

Quoted from §2.101 of the Federal Acquisition Regulation.

Termination for Default, Contracts
“Termination for default” means the exercise of the Government’s right to completely or partially terminate a contract because of the contractor’s actual or anticipated failure to perform its contractual obligations.

Quoted from §2.101 of the Federal Acquisition Regulation.
Termination of a Grant
For information about the termination of a grant, see §8.52 and §12.13.3 of the NIH Grants Policy Statement.
See: Termination
Termination of Support
See: Termination
Terms and Conditions of Award
All legal requirements imposed on a grant by NIH, whether based on statue, regulation, policy, or other document referenced in the grant award, or specified by the grant award document itself. The Notice of Award may include both standard and special conditions that are considered necessary to attain the grant's objectives, facilitate post award administration of the grant, conserve grant funds, or otherwise protect the Federal Government's interests.

Quoted from the NIH OER Glossary & Acronym List.

The Cancer Genome Atlas TCGA  
A comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing.

For additional information visit The Cancer Genome Atlas website.

The Career Enhancement Award K18  
Provides either full-time or part-time support for experienced scientists who wish to broaden their scientific capabilities or to make changes in their research careers by acquiring new research skills or knowledge. Career enhancement experiences supported by this award should usually last no more than one year.

For additional information, visit the NCI Grant Activity Codes/Mechanisms webpage.

The Transition Career Development Award K22  
The NCI Transition Career Development Award (K22) supports mentored, non-independent investigators ready to transition to independent academic faculty positions.

For additional information, visit the NCI Grant Activity Codes/Mechanisms webpage.

Third-Party In-Kind Contribution
The value of non-cash contributions (i.e., property or services) that: (1) Benefit a federally assisted project or program; and (2) Are contributed by non-Federal third parties, without charge, to a non- Federal entity under a Federal award.

Quoted from the NIH OER Glossary & Acronym List.

Tissue Array Research Program TARP  
The development and distribution of multitumor tissue microarray slides and related technologies to cancer research investigators.

For additional information, visit the Tissue Array Research Program (TARP) webpage.

Total Costs
The total allowable costs (both direct costs and F&A costs) incurred by the recipient to carry out a grant-supported project or activity. Total project costs include costs charged to the NIH grant and costs borne by the recipient to satisfy a matching or cost-sharing requirement.

Quoted from the NIH OER Glossary & Acronym List.

Total Costs, Entire Project Section
The Total Costs, Entire Project Period Section is where all values on the are automatically calculated, and the fields are pre-populated on the G.320 - PHS 398 Modular Budget Form.
See Also: Budget for Entire Proposed Period of Support Form
Total Direct Costs TDC  
All costs associated with a project exclusive of indirect costs. See §G. of the G.300 – R&R Budget Form and §A. of the G.320 – PHS 398 Modular Budget Form.
Total Project Costs
See: Total Costs
Track Record
The history of accomplishment (publications, funding, etc.) of an investigator.
Traditional Research Project Grant Application or Award
See: Research Project (R01) Grant
Training Awards
Awards designed to support the research training of scientists for careers in the biomedical and behavioral sciences, as well as help professional schools to establish, expand, or improve programs of continuing professional education. Training awards consist of institutional training grants (T) and individual fellowships (F). Go to NIH Research Training Opportunities.

Quoted from the NIH OER Glossary & Acronym List.

Training Grants
T or F series grants.

For additional information, visit the NCI Training webpage.

Transdisciplinary Research on Energetics and Cancer TREC  
The Transdisciplinary Research on Energetics and Cancer Centers initiative fosters collaboration across multiple disciplines and encompasses projects that cover the biology, genomics, and genetics of energy balance to behavioral, sociocultural, and environmental influences upon nutrition, physical activity, weight, energetics, and cancer risk. It provides training opportunities for new and established scientists who can carry out integrative research on energetics and energy balance.

For additional information, visit the NCI DCCPS TREC webpage.

Transdisciplinary Sciences
These include training and career development for those disciplines that are normally regarded as outside of traditional behavioral and biomedical cancer research and/or training and career development in those areas of cancer research that will require individuals to conduct their research within highly inter-disciplinary, collaborative team settings.
Transdisciplinary Tobacco Use Research Centers TTURC  
Facilitate a transdisciplinary approach to the full spectrum of basic and applied research on tobacco use to reduce the disease burden of tobacco use.

For additional information, visit the Transdisciplinary Tobacco Use Research Centers webpage.

Translational Research
Translational research includes two areas of translation. One is the process of applying discoveries generated during research in the laboratory, and in preclinical studies, to the development of trials and studies in humans. The second area of translation concerns research aimed at enhancing the adoption of best practices in the community. Cost-effectiveness of prevention and treatment strategies is also an important part of translational science.

Quoted from the NIH OER Glossary & Acronym List.

Translational Research Working Group TRWG  
The Translational Research Working Group (TRWG) was established in the summer of 2005 to conduct a discussion with the broader cancer research community and develop recommendations about how the National Cancer Institute (NCI) can best organize its investment to further "translational research."

For additional information, visit the NCI BBRB TRWG webpage.

Travel Management Center TMC  
As of June 5, 2015 the NIH Travel Management Center (TMC) Liaison duties were transfered from ORS to the NBS Travel Team.
Treatment Group
See: Experimental Group
See Also: Control Group
Treatment Investigational New Drug IND  
The treatment IND [21 CFR 312.34 and 312.35] is a mechanism for providing eligible subjects with investigational drugs for the treatment of serious and life-threatening illnesses for which there are no satisfactory alternative treatments. A treatment IND may be granted after sufficient data have been collected to show that the drug "may be effective" and does not have unreasonable risks. Because data related to safety and side effects are collected, treatment INDs also serve to expand the body of knowledge about the drug.

For additional information, visit the FDA's Treatment Use of Investigational Drugs – Information Sheet webpage.

See Also: Compassionate Use Trial
Treatment Trials
Most cancer clinical trials are treatment studies that involve people who have cancer. These trials test new treatments or new ways of using existing treatments, such as new:
  • Drugs,
  • Vaccines,
  • Approaches to surgery or radiation therapy, and
  • Combinations of treatments, including some that work to boost your immune system to help fight the cancer.

For additional information, visit the NCI Types of Clinical Trials webpage.

Triage
The assigning of priority order to projects on the basis of where funds and other resources can be best used, are most needed, or are most likely to achieve success.
See: Streamlined Review
Trial Sponsor
See: Clinical Trial Sponsor