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Current and Recent NCI and Trans-NIH Initiatives (R21)
Initiatives that are active or have expired within the last 3 months (and associated notices)
 
2024 Active  Requests for Applications (RFA's)
RFA No. and Title Status - Expiration
CA24-016 Development of Innovative Informatics Methods and Algorithms for Cancer Research and Management (R21 Clinical Trial Optional)ACTIVE - NOV 16, 2024
 
2024 Active  Program Announcements (PAs)
PA No. and Title Status - Expiration
PAR24-039 Exploratory Grant Award to Promote Workforce Diversity in Basic Cancer Research (R21 Clinical Trial Not Allowed)ACTIVE - NOV 18, 2026
 
2024 Active  Trans-NIH Program Announcements (PAs)
PA No. and Title Status - Expiration
PAR24-161 New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)ACTIVE - MAY 08, 2027
PAR24-092 Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)ACTIVE - MAY 08, 2027
 
 
 
 
 
2023 Active  Trans-NIH Requests for Applications (RFA's)
RFA No. and Title Status - Expiration
HG23-033 Advancing Genomic Medicine Research (R21 Clinical Trial Optional)ACTIVE - FEB 12, 2025
OD23-013 Understanding Chronic Conditions Understudied Among Women (R21 Clinical Trial Optional)ACTIVE - JUN 21, 2024
 
2023 Active  Program Announcements (PAs)
PA No. and Title Status - Expiration
PAR23-280 Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)ACTIVE - JAN 08, 2027
PAR23-255 Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)ACTIVE - SEP 08, 2026
PAR23-152 Impacts of climate change across the cancer control continuum (R21 Clinical Trial Optional)ACTIVE - MAY 08, 2026
PAR23-056 Co-infection and Cancer (R21 Clinical Trial Not Allowed)ACTIVE - NOV 17, 2025
 
2023 Active  Trans-NIH Program Announcements (PAs)
PA No. and Title Status - Expiration
PAR23-318 Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional)ACTIVE - MAR 21, 2026
PAR23-299 Intervention Research to Improve Native American Health (R21 Clinical Trials Optional)ACTIVE - JAN 08, 2027
PAR23-294 Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)ACTIVE - NOV 19, 2026
PAR23-191 HIV-associated Non-Communicable Diseases Research at Low- and Middle-Income Country Institutions (R21 Clinical Trial Optional)ACTIVE - DEC 09, 2025
 
 
 
 
 
2022 Active  Trans-NIH Requests for Applications (RFA's)
RFA No. and Title Status - Expiration
OD22-007 INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed)ACTIVE - JUL 02, 2024
 
2022 Active  Program Announcements (PAs)
PA No. and Title Status - Expiration
PAR22-219 Biology of Bladder Cancer (R21 Clinical Trial Optional)ACTIVE - SEP 08, 2025
PAR22-216 NCI Clinical and Translational Exploratory/Developmental Studies (R21 Clinical Trial Optional)ACTIVE - JUL 02, 2025
PAR22-199 Precision Approaches in Radiation Synthetic Combinations (PAIRS, R21 Clinical Trial Optional)ACTIVE - SEP 08, 2025
PAR22-165 Innovative Approaches to Studying Cancer Communication in the New Information Ecosystem (R21 Clinical Trial Optional)ACTIVE - SEP 08, 2025
PAR22-140 Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) (R21 Clinical Trial Not Allowed)ACTIVE - MAY 08, 2025
PAR22-109 Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)ACTIVE - MAY 08, 2025
PAR22-091 Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)ACTIVE - JAN 08, 2025
PAR22-090 Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)ACTIVE - JAN 08, 2025
PAR22-086 Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R21 Clinical Trial Not Allowed)ACTIVE - MAY 08, 2025
PAR22-084 Epidemiologic Research on Emerging Risk Factors and Liver Cancer Susceptibility (R21 Clinical Trial Not Allowed)ACTIVE - MAY 08, 2025
PAR22-062 Modulating Human Microbiome Function to Enhance Immune Responses Against Cancer (R21 Clinical Trial Not Allowed)ACTIVE - JAN 08, 2025
 
2022 Active  Trans-NIH Program Announcements (PAs)
PA No. and Title Status - Expiration
PAR22-126 Technology Development Research for Establishing Feasibility and Proof of Concept (R21 - Clinical Trial Not Allowed)ACTIVE - MAY 08, 2025
 
 
 
 
 
2021 Active  Trans-NIH Requests for Applications (RFA's)
RFA No. and Title Status - Expiration
OD21-007 INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Exploratory/Developmental Research Grant Award (R21 Clinical Trial Not Allowed)ACTIVE - JUL 04, 2024
 
2021 Active  Program Announcements (PAs)
PA No. and Title Status - Expiration
PAR21-341 Exploratory Grants in Cancer Control (R21 Clinical Trial Optional)ACTIVE - OCT 09, 2024
PAR21-332 Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21 Clinical Trial Not Allowed)ACTIVE - SEP 08, 2024
PAR21-323 Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)ACTIVE - SEP 08, 2024